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Shareef, M.M., Kokkinakis, D.M. and  Ahmed,  M.M. Potential Use of MDA-7 as a Biological Adjuvant for Radiation Therapy.Cancer Biol Ther. 2004 Aug 15;3(8). [Epub ahead of print]

Arnold, S.M., Regine, W.F., Ahmed, M.M., Valentino, J., Spring, P., Kudrimoti, M., Kenady, D., Desimone, P. and Mohiuddin, M. Low-dose fractionated radiation as a chemopotentiator of neoadjuvant paclitaxel and carboplatin for locally advanced squamous cell carcinoma of the head and neck: results of a new treatment paradigm. Int J Radiat Oncol Biol Phys. 2004 Apr 1;58(5):1411-7.

Ranga, R.S., Girija, R., Nur-e-Alam, M., Sathishkumar, S., Akbarsha, M.A., Thirugnanam, S., Rohr, J., Ahmed, M.M. and  Chendil, D.Rasagenthi lehyam (RL) a novel complementary and alternative medicine for prostate cancer.Cancer Chemother Pharmacol. 2004 Jul;54(1):7-15. Epub 2004 Mar 24.

Chendil, D., Ranga, R.S., Meigooni, D., Sathishkumar, S., Ahmed., M.M.  Curcumin confers radiosensitizing effect in prostate cancer cell line PC-3. Oncogene. 2004 Feb 26;23(8):1599-607.

Ahmed, M. M. Regulation of radiation-induced apoptosis by early growth response-1 gene in solid tumors. Current Cancer Drug Targets, 4: 43-52, 2004.

Spring, P.M., Arnold, S.M., Dimova, N., Shajahan, S., Brown, B., Dey, S., Lele, S., Valentino, J.,  Jones, R., Mohiuddin, M. and Ahmed, M.M.  Low Dose Fractionated Radiation Potentiates the Effects of Taxotere in Nude Mice Xenografts of squamous cell carcinoma of head and neck.  Cell Cycle. 2004 Apr;3(4):479-85. Epub 2004 Apr 01.

Rushing, R. S., Shajahan, S., Chendil, D., Wilder, J. L., Pulliam, J., Lee, E. Y., Ueland, F. R., van Nagell, J. R., Ahmed, M. M., and Lele, S. M. Uterine sarcomas express KIT protein but lack mutation(s) in exon 11 or 17 of c-KIT. Gynecologic Oncology, 91: 9-14, 2003.

Kokkinakis, D.M., Ahmed, M.M., Chendil, D., Moschel, R.C. and Pegg, A.E. Sensitization of pancreatic  tumor  xenografts  to  carmustine and temozolomide by inactivation of their  O6-Methylguanine-DNA methyltransferase with O6-benzylguanine or O6-benzyl-2-deoxyguanosine. Clinical Cancer Res, 9: 3801-3807, 2003.

Halepota, M., Mohiuddin, M., Desimone, P. and Ahmed, M.M.  Durable local responses with subtherapeutic doses of concurrent radiation and gemcitabine in a patient with refractory Hodgkin?s disease.  Clinical Advances in Hematology & Oncology, 1 (7): 413-415, 2003.

Dey, S., Spring, P. M., Arnold, S., Valentino, J., Chendil, D., Regine, W. F., Mohiuddin, M., and Ahmed, M. M. Low dose fractionated radiation potentiates the effects of paclitaxel in wild-type and mutant p53 head and neck tumor cell lines. Clinical Cancer Res, 9, 1557-1565, 2003.

Mayhew, C.N., Mampuru, L.J., Chendil, D., Ahmed, M.M., Phillips, J.D., Greenberg, R.N., Elford, H.L. and Gallicchio, V.S. Supression of retrovirus-induced immunodeficiency disease (murine AIDS) by trimidox and didox: novel ribonucleotide reductase inhibitors with less bone marrow toxicity than hydroxyurea. Antiviral Res., 56: 167-181, 2002.

Alcock, R. A., Dey, S., Chendil, D., Inayat, M. S., Mohiuddin, M., Hartman, G., Chatfield, L. K., Gallicchio, V. S., and Ahmed, M. M. Farnesyltransferase inhibitor (L-744,832) restores TGF-beta type II receptor expression and enhances radiation sensitivity in K-ras mutant pancreatic cancer cell line MIA PaCa-2. Oncogene, 21: 7883-7890, 2002.

Inayat, M. S., Chendil, D., Mohiuddin, M., Elford, H. L., Gallicchio, V. S., and Ahmed, M. M. Didox A Novel Ribonucleotide Reductase Inhibitor overcomes bcl-2 mediated radiation resistance in prostate cancer cell line PC-3. Cancer Biol Ther, 1: 539-545, 2002 (see editorial commentary).

Siddiqua, A., Chendil, D., Rowland, R., Meigooni, A.S., St Clair, W.B., Mohiuddin, M. and Ahmed, M.M. Increased expression of PSA mRNA during the brachytherapy procedure in peripheral blood of patients with prostate cancer. Urology 60 (2): 270-275, 2002.

Mohiuddin, M., Chendil, D., Dey, D., Alcock, R.A., Regine, W., Mohiuddin, M. and Ahmed, M.M. Influence of p53 status on radiation and 5-Flourouracil synergy in pancreatic cancer cells.  Anticancer Research 22 (2): 825-830, 2002.

Ahmed, M.M., Satishkumar, S., Fruitwala, S.M., Venkatasubbarao, K., Meigooni, A.S. and Mohiuddin, M.  Spatially fractionated (GRID) radiation: TNF-a mediated therapeutic gain in enhanced cell killing of radioresistant tumor cells. Technology in Cancer Research Treatment 1 (2):141-147, 2002.

Chendil, D., Das, A., Dey, S., Mohiuddin, M., and Ahmed, M.M. Par-4, a pro-apoptotic gene, inhibits NFkB activity resulting in the repression of radiation-induced bcl-2 expression leading to induction of radiosensitivity in human prostate cancer cells PC-3. Cancer Biology and Therapy 1 (2) 152-160, 2002.

Ahmed, M.M., Alcock, R.A., Chendil, D., Dey, S., Das, A., Venkatasubbarao, K., Mohiuddin, M., Sun, L., Strodel W.E. and Freeman, J.W.  Restoration of TGF-b signaling enhances radiosensitivity by altering the bcl-2: bax ratio in the p53 mutant pancreatic cancer cell line MIA PaCa-2.  J Biological Chemistry , 277 (3): 2234-2246, 2002..

Ozkan, L., Egeli, U., Tunca, B., Aydemit, N., Cecener, G., Ergul, E., Akpinar, G., Ergul, E., Cimen, C., Ozuysal, S., Kahraman-Cetintas, S., Engin, K. and Ahmed, M.M.  Investigation of genotoxic effect of Taxol plus radiation on mice bone marrow cells.  Teratogenesis, Carcinogenesis, and Mutagenesis 22: 1-11, 2002. 

Ahmed, M.M., Chendil, D., Lele, S., Venkatasubbarao, K., Dey, S., Ritter, M., Rowland, R. and Mohiuddin, M.  Early growth response-1 gene : potential radiation response gene marker in prostate cancer.  Am J of Clin Oncol (CCT) 24 (5): 500-505, 2001.

Ozkan, L., Ozuysal, S., Egeli, U., Adim, S.B., Tunca, B., Aydemit, N., Cecener, G., Ergul, E., Akpinar, G., Cimen, C., Engin, K. and Ahmed, M.M.  Effects of taxol plus radiation on the apoptotic and mitotic indices of mouse intestinal crypt cells.  Journal of Cancer Res and Clin Oncol 127: 127-433, 2001.

Das, A.,  Chendil, D., Dey, S., Mohiuddin, M., Mohiuddin, M., Milbrandt, J., Rangnekar, V.M and Ahmed, M.M. Ionizing radiation down-regulates p53 protein in primary Egr-1-/- mouse embryonic fibroblast cells causing enhanced resistance to apoptosis. J Biological Chemistry  276 (5):3279-3286, 2001.

Chendil, D., Oakes, R., Alcock, R., Patel, N., Mayhew, C., Gallicchio, V.S., Mohiuddin, M. and Ahmed, M.M. Fractionated radiation enhances radiosensitization effect of paclitaxel in colorectal tumor cells with mutant p53 phenotype. Cancer  89:1893-1900, 2000

Fralix, K.D,  Ahmed, M.M., Mattingly, C., Swiderski, C., McGrath, P.,  Venkatasubbarao, K., Kamada, N., Mohiuddin, M., Strodel, W.E. and Freeman, J.W.  Characterization of newly established human pancreatic carcinoma cell line, UK Pan-1.  Cancer 88:2010-2021, 2000.

Venkatasubbarao, K.,  Ahmed, M.M., Mohiuddin, M.,  Swiderski, S., Lee, E., Gower, W. R. Jr., Salhab, K.F.,  McGrath, P.,  Strodel, W.  and  Freeman, J.W. Differential Expression of Transforming Growth Factor b Receptors in Human Pancreatic Adenocarcinoma.  Anticancer Research 20:43-52, 2000.

Mohiuddin, M., Fujita, M., Regine, W.F., Megooni, A.S., Ibbott, G.S. and Ahmed, M.M.  High dose spatially fractionated radiation (GRID): A new paradigm in the management of advanced cancers. Int. J. Radiat. Oncol. Biol. Phy , 44 (5): 1999.

Qui, G., Ahmed, M.M., Sells, S.F., Cookson, M.S., Mohiuddin, M., Weinstein, M.H. and Rangnekar, V.M.  Mutually exclusive expression pattern of Bcl-2 and Par-4 in human prostate tumors consistent with down regulation of Bcl-2 by Par-4.  Oncogene, 18:623-631,1999.

Venkatasubbarao, K., Ahmed, M.M., Swiderski, C., Harp, C., Lee, E., McGrath, P.,  Mohiuddin, M., Strodel, W., and Freeman, J.W.  Novel mutations in the polyadenine tract of the transforming growth factor-b type II receptor gene are found in a subpopulation of human pancreatic adenocarcinomas.  Genes, Chromosomes & Cancer  22:138-144, 1998.

Ahmed, M.M., Sells, S., Venkatasubbarao, K.,   Fruitwala, S.,  Muthukkumar, S., Harp, C.,  Mohiuddin, M., and Rangnekar, V. Ionizing radiation-inducible apoptosis in the absence of p53 linked to transcription factor EGR-1. J Biological Chemistry   272(52): 33056-33061, 1997.         

Kokkinakis, D.M., Ahmed, M.M., Delgado, R., Fruitwala, M.A., Mohiuddin, M. and Albores-Saavedra, J.  Role of O6-methyl guanine-DNA methyltransferase in the resistance of pancreatic tumors to DNA alkylating agents. Cancer Research  57 (23):5360-5368, 1997

Mohiuddin, M. and Ahmed, M.M.  Critical issues in the evolving management of rectal cancer.  Seminars Oncol 24 (6):732-744, 1997.

Ahmed, M.M.,Venkatasubbarao, K., Fruitwala, S., Muthukkumar, S.,   Wood, Jr.P., Sells, S.F., Mohiuddin, M., and Rangnekar, V.M.  EGR-1 induction is required for maximal radio sensitivity in A375-C6 melanoma cells.   J Biological Chemistry   271 (46): 29231-29237, 1996.

Lee, J.H., Lee, S.K., Yang, M.H., Ahmed, M.M., Mohiuddin, M, Lee, E.Y.  Expression and mutation of H-ras in uterine cervical cancer.  Gynecologic Oncology 62 : 49-54, 1996.

Mohiuddin, M., Ahmed, M.M., Venkatasubbarao, K.  c-Ki-ras mutations in     peripheral blood of pancreatic cancer patients: A marker for early tumor metastasis.   Int. J. Radiat. Oncol. Biol. Phys 34 (1): 161-166, 1995.










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